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A Low-Activity Polymorphic Variant of Human NEIL2 DNA Glycosylase

Human NEIL2 DNA glycosylase (hNEIL2) is a base excision repair protein that removes oxidative lesions from DNA. A distinctive feature of hNEIL2 is its preference for the lesions in bubbles and other non-canonical DNA structures. Although a number of associations of polymorphisms in the hNEIL2 gene w...

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Detalles Bibliográficos
Autores principales: Kakhkharova, Zarina I., Zharkov, Dmitry O., Grin, Inga R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879280/
https://www.ncbi.nlm.nih.gov/pubmed/35216329
http://dx.doi.org/10.3390/ijms23042212