Cargando…
A Low-Activity Polymorphic Variant of Human NEIL2 DNA Glycosylase
Human NEIL2 DNA glycosylase (hNEIL2) is a base excision repair protein that removes oxidative lesions from DNA. A distinctive feature of hNEIL2 is its preference for the lesions in bubbles and other non-canonical DNA structures. Although a number of associations of polymorphisms in the hNEIL2 gene w...
Autores principales: | Kakhkharova, Zarina I., Zharkov, Dmitry O., Grin, Inga R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879280/ https://www.ncbi.nlm.nih.gov/pubmed/35216329 http://dx.doi.org/10.3390/ijms23042212 |
Ejemplares similares
-
The Biochemical Role of the Human NEIL1 and NEIL3 DNA Glycosylases on Model DNA Replication Forks
por: Albelazi, Mustafa S., et al.
Publicado: (2019) -
Noncatalytic Domains in DNA Glycosylases
por: Torgasheva, Natalia A., et al.
Publicado: (2022) -
Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer
por: Shinmura, Kazuya, et al.
Publicado: (2016) -
Displacement of Slow-Turnover DNA Glycosylases by Molecular Traffic on DNA
por: Yudkina, Anna V., et al.
Publicado: (2020) -
Evolutionary Origins of DNA Repair Pathways: Role of Oxygen Catastrophe in the Emergence of DNA Glycosylases
por: Prorok, Paulina, et al.
Publicado: (2021)