Formulation Approaches for Improving the Dissolution Behavior and Bioavailability of Tolvaptan Using SMEDDS

Tolvaptan, a selective vasopressin receptor antagonist, is a Class IV agent of Biopharmaceutical Classification System (BCS). To improve bioavailability after oral administration, the new tolvaptan-loaded self-microemulsifying drug delivery system (SMEDDS) was further optimized using a “design of th...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Hwa, Lee, Gye-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879311/
https://www.ncbi.nlm.nih.gov/pubmed/35214147
http://dx.doi.org/10.3390/pharmaceutics14020415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879311/
https://www.ncbi.nlm.nih.gov/pubmed/35214147
http://dx.doi.org/10.3390/pharmaceutics14020415

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