Evaluation of the Safety, Tolerability and Immunogenicity of ShigETEC, an Oral Live Attenuated Shigella-ETEC Vaccine in Placebo-Controlled Randomized Phase 1 Trial

Background: Shigella spp. and enterotoxigenic Escherichia coli (ETEC) cause high morbidity and mortality worldwide, yet no licensed vaccines are available to prevent corresponding infections. A live attenuated non-invasive Shigella vaccine strain lacking LPS O-antigen and expressing the ETEC toxoids...

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Detalles Bibliográficos
Autores principales: Girardi, Petra, Harutyunyan, Shushan, Neuhauser, Irene, Glaninger, Katharina, Korda, Orsolya, Nagy, Gábor, Nagy, Eszter, Szijártó, Valéria, Pall, Denes, Szarka, Krisztina, Kardos, Gábor, Henics, Tamás, Malinoski, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879453/
https://www.ncbi.nlm.nih.gov/pubmed/35214798
http://dx.doi.org/10.3390/vaccines10020340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879453/
https://www.ncbi.nlm.nih.gov/pubmed/35214798
http://dx.doi.org/10.3390/vaccines10020340

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