Tissue Transglutaminase but Not Microbial Transglutaminase Is Inhibited by Exogenous Oxidative Substances in Celiac Disease

Enzymatic modification of gliadin peptides by human transglutaminase 2 (TG2) is a central step in celiac disease (CD) pathogenesis. Microbial transglutaminase (mTG) mimics the enzymatic function of TG2 and might play a role in CD. TG2 is inhibited by endogenous oxidative endoplasmic reticulum-reside...

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Detalles Bibliográficos
Autores principales: Stricker, Sebastian, Rudloff, Silvia, De Laffolie, Jan, Zimmer, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879474/
https://www.ncbi.nlm.nih.gov/pubmed/35216364
http://dx.doi.org/10.3390/ijms23042248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879474/
https://www.ncbi.nlm.nih.gov/pubmed/35216364
http://dx.doi.org/10.3390/ijms23042248

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