Effect of Progranulin on Proliferation and Differentiation of Neural Stem/Progenitor Cells after Oxygen/Glucose Deprivation

We previously demonstrated that sivelestat, a selective neutrophil elastase inhibitor, attenuates the cleavage of progranulin (PGRN) and ischemia-induced cell injury in the brain. To obtain further insight into the role of PGRN, in the present study we evaluated the direct effects of sivelestat and...

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Detalles Bibliográficos
Autores principales: Horinokita, Ichiro, Hayashi, Hideki, Nagatomo, Takamasa, Fushiki, Yuna, Iwatani, Yui, Takagi, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879483/
https://www.ncbi.nlm.nih.gov/pubmed/35216064
http://dx.doi.org/10.3390/ijms23041949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879483/
https://www.ncbi.nlm.nih.gov/pubmed/35216064
http://dx.doi.org/10.3390/ijms23041949

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