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Effect of Progranulin on Proliferation and Differentiation of Neural Stem/Progenitor Cells after Oxygen/Glucose Deprivation

We previously demonstrated that sivelestat, a selective neutrophil elastase inhibitor, attenuates the cleavage of progranulin (PGRN) and ischemia-induced cell injury in the brain. To obtain further insight into the role of PGRN, in the present study we evaluated the direct effects of sivelestat and...

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Detalles Bibliográficos
Autores principales:	Horinokita, Ichiro, Hayashi, Hideki, Nagatomo, Takamasa, Fushiki, Yuna, Iwatani, Yui, Takagi, Norio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879483/ https://www.ncbi.nlm.nih.gov/pubmed/35216064 http://dx.doi.org/10.3390/ijms23041949

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