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Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism

Zebrafish (ZF; Danio rerio) larvae have become a popular in vivo model in drug metabolism studies. Here, we investigated the metabolism of methyl 2-[1-(4-fluorobutyl)-1H-indazole-3-carboxamido]-3,3-dimethylbutanoate (4F-MDMB-BINACA) in ZF larvae after direct administration of the cannabinoid via mic...

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Detalles Bibliográficos
Autores principales: Park, Yu Mi, Dahlem, Charlotte, Meyer, Markus R., Kiemer, Alexandra K., Müller, Rolf, Herrmann, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879502/
https://www.ncbi.nlm.nih.gov/pubmed/35209079
http://dx.doi.org/10.3390/molecules27041290