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Multiplexed Genome Editing for Efficient Phenotypic Screening in Zebrafish

Zebrafish are widely used to investigate candidate genes for human diseases. While the emergence of CRISPR-Cas9 technology has revolutionized gene editing, the use of individual guide RNAs limits the efficiency and application of this technology in functional genetics research. Multiplexed genome ed...

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Detalles Bibliográficos
Autores principales: Guo, Shuyu, Gao, Ge, Zhang, Cuizhen, Peng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879510/
https://www.ncbi.nlm.nih.gov/pubmed/35202345
http://dx.doi.org/10.3390/vetsci9020092