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Multiplexed Genome Editing for Efficient Phenotypic Screening in Zebrafish
Zebrafish are widely used to investigate candidate genes for human diseases. While the emergence of CRISPR-Cas9 technology has revolutionized gene editing, the use of individual guide RNAs limits the efficiency and application of this technology in functional genetics research. Multiplexed genome ed...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879510/ https://www.ncbi.nlm.nih.gov/pubmed/35202345 http://dx.doi.org/10.3390/vetsci9020092 |