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A Novel Anti-B7-H3 × Anti-CD3 Bispecific Antibody with Potent Antitumor Activity

B7-H3 plays an important role in tumor apoptosis, proliferation, adhesion, angiogenesis, invasion, migration, and evasion of immune surveillance. It is overexpressed in various human solid tumor tissues. In patients, B7-H3 overexpression correlates with advanced stages, poor clinical outcomes, and r...

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Detalles Bibliográficos
Autores principales: Feng, Yan, Xie, Kun, Yin, Yanxin, Li, Bingyu, Pi, Chenyu, Xu, Xiaoqing, Huang, Tao, Zhang, Jingming, Wang, Bo, Gu, Hua, Fang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879513/
https://www.ncbi.nlm.nih.gov/pubmed/35207448
http://dx.doi.org/10.3390/life12020157