Thermodynamic Solubility Profile of Temozolomide in Different Commonly Used Pharmaceutical Solvents

The solubility parameters, and solution thermodynamics of temozolomide (TMZ) in 10 frequently used solvents were examined at five different temperatures. The maximum mole fraction solubility of TMZ was ascertained in dimethyl sulfoxide (1.35 × 10(−2)), followed by that in polyethylene glycol-400 (3....

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Detalles Bibliográficos
Autores principales: Ahad, Abdul, Shakeel, Faiyaz, Raish, Mohammad, Ahmad, Ajaz, Bin Jardan, Yousef A., Al-Jenoobi, Fahad I., Al-Mohizea, Abdullah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879539/
https://www.ncbi.nlm.nih.gov/pubmed/35209225
http://dx.doi.org/10.3390/molecules27041437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879539/
https://www.ncbi.nlm.nih.gov/pubmed/35209225
http://dx.doi.org/10.3390/molecules27041437

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