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A sandwich ELISA kit reveals marked elevation of titin N‐terminal fragment levels in the urine of mdx mice

The mdx mouse is a model of Duchenne muscular dystrophy (DMD), a fatal progressive muscle wasting disease caused by dystrophin deficiency, and is used most widely in preclinical studies. Mice with dystrophin deficiency, however, show milder muscle strength phenotypes than humans. In human, the intro...

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Detalles Bibliográficos
Autores principales: Shirakawa, Taku, Ikushima, Ayumu, Maruyama, Nobuhiro, Nambu, Yoshinori, Awano, Hiroyuki, Osawa, Kayo, Nirasawa, Kei, Negishi, Yoichi, Nishio, Hisahide, Fukushima, Shoji, Matsuo, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879618/
https://www.ncbi.nlm.nih.gov/pubmed/35229992
http://dx.doi.org/10.1002/ame2.12204