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Deficient Rnf43 potentiates hyperactive Kras‐mediated pancreatic preneoplasia initiation and malignant transformation

BACKGROUND: Largely due to incidental detection, asymptomatic pancreatic cystic lesions (PCLs) have become prevalent in recent years. Among them, intraductal papillary mucinous neoplasm (IPMN) infrequently advances to pancreatic ductal adenocarcinoma (PDAC). Conservative surveillance versus surgical...

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Detalles Bibliográficos
Autores principales: Zhou, Xian, Sun, Zhichao, Zhang, Mengdi, Qu, Xiaoyu, Yang, Shuhui, Wang, Lianmei, Jing, Yanling, Li, Li, Deng, Weiwei, Liu, Fangming, Di, Jin, Chen, Jie, Wu, Jian, Zhang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879633/
https://www.ncbi.nlm.nih.gov/pubmed/35229994
http://dx.doi.org/10.1002/ame2.12203