Characterizing the Physicochemical Properties of Two Weakly Basic Drugs and the Precipitates Obtained from Biorelevant Media

Generally, some weakly basic insoluble drugs will undergo precipitate and redissolution after emptying from the stomach to the small intestinal, resulting in the limited ability to predict the absorption characteristics of compounds in advance. Absorption is determined by the solubility and permeabi...

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Detalles Bibliográficos
Autores principales: Zhang, Miao, Wu, Bin, Zhang, Shudong, Wang, Lin, Hu, Qin, Liu, Dongyang, Chen, Xijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879660/
https://www.ncbi.nlm.nih.gov/pubmed/35214062
http://dx.doi.org/10.3390/pharmaceutics14020330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879660/
https://www.ncbi.nlm.nih.gov/pubmed/35214062
http://dx.doi.org/10.3390/pharmaceutics14020330

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