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Characterizing the Physicochemical Properties of Two Weakly Basic Drugs and the Precipitates Obtained from Biorelevant Media
Generally, some weakly basic insoluble drugs will undergo precipitate and redissolution after emptying from the stomach to the small intestinal, resulting in the limited ability to predict the absorption characteristics of compounds in advance. Absorption is determined by the solubility and permeabi...
Autores principales: | Zhang, Miao, Wu, Bin, Zhang, Shudong, Wang, Lin, Hu, Qin, Liu, Dongyang, Chen, Xijing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879660/ https://www.ncbi.nlm.nih.gov/pubmed/35214062 http://dx.doi.org/10.3390/pharmaceutics14020330 |
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