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Study of the Structure–Activity Relationship of an Anti-Dormant Mycobacterial Substance 3-(Phenethylamino)Demethyl(oxy)aaptamine to Create a Probe Molecule for Detecting Its Target Protein

The current tuberculosis treatment regimen is long and complex, and its failure leads to relapse and emergence of drug resistance. One of the major reasons underlying the extended chemotherapeutic regimen is the ability of Mycobacterium tuberculosis to attain a dormant state. Therefore, the identifi...

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Detalles Bibliográficos
Autores principales: Sumii, Yuji, Kamiya, Kentaro, Nakamura, Takehiko, Tanaka, Kenta, Kaji, Takumi, Mukomura, Junya, Kotoku, Naoyuki, Arai, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879696/
https://www.ncbi.nlm.nih.gov/pubmed/35200628
http://dx.doi.org/10.3390/md20020098