Cargando…
Study of the Structure–Activity Relationship of an Anti-Dormant Mycobacterial Substance 3-(Phenethylamino)Demethyl(oxy)aaptamine to Create a Probe Molecule for Detecting Its Target Protein
The current tuberculosis treatment regimen is long and complex, and its failure leads to relapse and emergence of drug resistance. One of the major reasons underlying the extended chemotherapeutic regimen is the ability of Mycobacterium tuberculosis to attain a dormant state. Therefore, the identifi...
Autores principales: | Sumii, Yuji, Kamiya, Kentaro, Nakamura, Takehiko, Tanaka, Kenta, Kaji, Takumi, Mukomura, Junya, Kotoku, Naoyuki, Arai, Masayoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879696/ https://www.ncbi.nlm.nih.gov/pubmed/35200628 http://dx.doi.org/10.3390/md20020098 |
Ejemplares similares
-
Oxidative Cyclization at ortho-Position of Phenol: Improved Total Synthesis of 3-(Phenethylamino)demethyl(oxy)aaptamine
por: Nakatani, Yuki, et al.
Publicado: (2023) -
Anti-Mycobacterial N-(2-Arylethyl)quinolin-3-amines Inspired by Marine Sponge-Derived Alkaloid
por: Mukomura, Junya, et al.
Publicado: (2022) -
Structure-Activity Relationship and in Vivo Anti-Tumor Evaluations of Dictyoceratin-A and -C, Hypoxia-Selective Growth Inhibitors from Marine Sponge
por: Sumii, Yuji, et al.
Publicado: (2015) -
Cytotoxic Aaptamines from Malaysian Aaptos aaptos
por: Shaari, Khozirah, et al.
Publicado: (2008) -
Target Identification of the Marine Natural Products Dictyoceratin-A and -C as Selective Growth Inhibitors in Cancer Cells Adapted to Hypoxic Environments
por: Kawachi, Takashi, et al.
Publicado: (2019)