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Recombinant BCG Expressing the Subunit 1 of Pertussis Toxin Induces Innate Immune Memory and Confers Protection against Non-Related Pathogens

BCG has shown the ability to induce protection against unrelated pathogens, which likely depends on an immune mechanism known as innate immune memory or trained immunity. In this study, we evaluated the induction of innate memory by a recombinant BCG strain expressing the genetically detoxified S1 s...

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Detalles Bibliográficos
Autores principales: Kanno, Alex I., Boraschi, Diana, Leite, Luciana C. C., Rodriguez, Dunia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879706/
https://www.ncbi.nlm.nih.gov/pubmed/35214691
http://dx.doi.org/10.3390/vaccines10020234