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Recombinant BCG Expressing the Subunit 1 of Pertussis Toxin Induces Innate Immune Memory and Confers Protection against Non-Related Pathogens
BCG has shown the ability to induce protection against unrelated pathogens, which likely depends on an immune mechanism known as innate immune memory or trained immunity. In this study, we evaluated the induction of innate memory by a recombinant BCG strain expressing the genetically detoxified S1 s...
Autores principales: | Kanno, Alex I., Boraschi, Diana, Leite, Luciana C. C., Rodriguez, Dunia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879706/ https://www.ncbi.nlm.nih.gov/pubmed/35214691 http://dx.doi.org/10.3390/vaccines10020234 |
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