High Level of Pre-Treatment HIV-1 Drug Resistance and Its Association with HLA Class I-Mediated Restriction in the Pumwani Sex Worker Cohort

Background: We analyzed the prevalence of pre-antiretroviral therapy (ART) drug resistance mutations (DRMs) in a Kenyan population. We also examined whether host HLA class I genes influence the development of pre-ART DRMs. Methods: The HIV-1 proviral DNAs were amplified from blood samples of 266 ART...

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Detalles Bibliográficos
Autores principales: Willim, Rachel, Shadabi, Elnaz, Sampathkumar, Raghavan, Li, Lin, Balshaw, Robert, Kimani, Joshua, Plummer, Francis A., Luo, Ma, Liang, Binhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879707/
https://www.ncbi.nlm.nih.gov/pubmed/35215866
http://dx.doi.org/10.3390/v14020273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879707/
https://www.ncbi.nlm.nih.gov/pubmed/35215866
http://dx.doi.org/10.3390/v14020273

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