Cargando…

High Level of Pre-Treatment HIV-1 Drug Resistance and Its Association with HLA Class I-Mediated Restriction in the Pumwani Sex Worker Cohort

Background: We analyzed the prevalence of pre-antiretroviral therapy (ART) drug resistance mutations (DRMs) in a Kenyan population. We also examined whether host HLA class I genes influence the development of pre-ART DRMs. Methods: The HIV-1 proviral DNAs were amplified from blood samples of 266 ART...

Descripción completa

Detalles Bibliográficos
Autores principales:	Willim, Rachel, Shadabi, Elnaz, Sampathkumar, Raghavan, Li, Lin, Balshaw, Robert, Kimani, Joshua, Plummer, Francis A., Luo, Ma, Liang, Binhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879707/ https://www.ncbi.nlm.nih.gov/pubmed/35215866 http://dx.doi.org/10.3390/v14020273

Ejemplares similares

Influence of HLA Class I Haplotypes on HIV-1 Seroconversion and Disease Progression in Pumwani Sex Worker Cohort
por: Sampathkumar, Raghavan, et al.
Publicado: (2014)

HIV-1 Subtypes and 5′LTR-Leader Sequence Variants Correlate with Seroconversion Status in Pumwani Sex Worker Cohort
por: Sampathkumar, Raghavan, et al.
Publicado: (2017)

The frequencies of naturally occurring protease inhibitor resistance mutations in HIV proviral sequences of drug naïve sex workers in Nairobi, Kenya and their correlation with host immune response driven positively selected mutations in HIV-1
por: Sampathkumar, Raghavan, et al.
Publicado: (2014)

Naturally occurring protease inhibitor resistance mutations and their frequencies in HIV proviral sequences of drug-naïve sex workers in Nairobi, Kenya
por: Sampathkumar, Raghavan, et al.
Publicado: (2014)

Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response
por: Sampathkumar, Raghavan, et al.
Publicado: (2012)

Effect of Newborn Resuscitation Training on Health Worker Practices in Pumwani Hospital, Kenya
por: Opiyo, Newton, et al.
Publicado: (2008)

Age and menopause affect the expression of specific cytokines/chemokines in plasma and cervical lavage samples from female sex workers in Nairobi, Kenya
por: Sivro, Aida, et al.
Publicado: (2013)

HLA Class II Antigens and Their Interactive Effect on Perinatal Mother-To-Child HIV-1 Transmission
por: Luo, Ma, et al.
Publicado: (2015)

T cell immune quiescence as a contributor to resistance to infection among HIV Exposed Seronegative (HESN) commercial sex workers from Nairobi, Kenya
por: Fowke, KR, et al.
Publicado: (2012)

Depression during pregnancy and preterm delivery: a prospective cohort study among women attending antenatal clinic at Pumwani Maternity Hospital
por: Mochache, Kingi, et al.
Publicado: (2018)

Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
por: Dillard, Pierre, et al.
Publicado: (2021)

Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer
por: Matsuzaki, Junko, et al.
Publicado: (2022)

NFκB1 Polymorphisms Are Associated with Severe Influenza A (H1N1) Virus Infection in a Canadian Population
por: Mirzo, Suhrobjon Mullo, et al.
Publicado: (2022)

The Impact of Sex Work Interruption on Blood-Derived T Cells in Sex Workers from Nairobi, Kenya
por: Omollo, Kenneth, et al.
Publicado: (2016)

Folate deficiency and utilization of folic acid fortified flour among pregnant women attending antenatal clinic at Pumwani Maternity Hospital, Kenya, 2015
por: Mgamb, Elizabeth, et al.
Publicado: (2017)

Correction to: Depression during pregnancy and preterm delivery: a prospective cohort study among women attending antenatal clinic at Pumwani Maternity Hospital
por: Mochache, Kingi, et al.
Publicado: (2018)

Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA class I) allotypes
por: Olson, Eli, et al.
Publicado: (2023)

HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer
por: Ren, Yingxue, et al.
Publicado: (2020)

HLA Class I Restriction as a Possible Driving Force for Chikungunya Evolution
por: Tong, Joo Chuan, et al.
Publicado: (2010)

Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction
por: Klarenbeek, Paul L., et al.
Publicado: (2015)

HIV-infected sex workers with beneficial HLA-variants are potential hubs for selection of HIV-1 recombinants that may affect disease progression
por: Chang, Chih-Hao, et al.
Publicado: (2015)

Blunted IL17/IL22 and Pro-Inflammatory Cytokine Responses in the Genital Tract and Blood of HIV-Exposed, Seronegative Female Sex Workers in Kenya
por: Chege, Duncan, et al.
Publicado: (2012)

Does antiretroviral therapy initiation increase sexual risk taking in Kenyan female sex workers? A retrospective case–control study
por: Mawji, Elysha, et al.
Publicado: (2012)

The identification of HLA class II-restricted T cell epitopes to vaccinia virus membrane proteins
por: Kennedy, Richard B., et al.
Publicado: (2010)

Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor
por: Rühl, Geraldine, et al.
Publicado: (2016)

Immunogenicity of HLA Class I and II Double Restricted Influenza A-Derived Peptides
por: Pedersen, Sara Ram, et al.
Publicado: (2016)

Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes
por: Sedegah, Martha, et al.
Publicado: (2016)

Identification of Novel HLA Class II-Restricted Neoantigens Derived from Driver Mutations
por: Iiizumi, Susumu, et al.
Publicado: (2019)

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers
por: Nyanhete, Tinashe E., et al.
Publicado: (2019)

Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
por: Dillard, Pierre, et al.
Publicado: (2021)

Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
por: Aparicio, Belén, et al.
Publicado: (2022)

High level of plasma TILRR protein is associated with faster HIV seroconversion
por: Kashem, Mohammad Abul, et al.
Publicado: (2022)

Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers
por: Birse, Kenzie D. M., et al.
Publicado: (2015)

Microarray Analysis of HIV Resistant Female Sex Workers Reveal a Gene Expression Signature Pattern Reminiscent of a Lowered Immune Activation State
por: Songok, Elijah M., et al.
Publicado: (2012)

Identification of a specific HLA DR2 Ia molecule as a restriction element for measles virus-specific HLA class II-restricted cytotoxic T cell clones
Publicado: (1985)

Direct identification of HLA class I and class II-restricted T cell epitopes in pancreatic cancer tissues by mass spectrometry
por: Fujiwara, Kenji, et al.
Publicado: (2022)

Correction: Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers
por: Birse, Kenzie D. M., et al.
Publicado: (2015)

Human Leukocyte Antigen (HLA) Class I Restricted Epitope Discovery in Yellow Fewer and Dengue Viruses: Importance of HLA Binding Strength
por: Lund, Ole, et al.
Publicado: (2011)

Apparent lack of MHC restriction in binding of class I HLA molecules to solid-phase peptides
Publicado: (1990)

Correction: Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes
por: Sedegah, Martha, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_taubfn17vu6u1plokgo10tt4d6