Knockout of the P2Y(6) Receptor Prevents Peri-Infarct Neuronal Loss after Transient, Focal Ischemia in Mouse Brain

After stroke, there is a delayed neuronal loss in brain areas surrounding the infarct, which may in part be mediated by microglial phagocytosis of stressed neurons. Microglial phagocytosis of stressed or damaged neurons can be mediated by UDP released from stressed neurons activating the P2Y(6) rece...

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Detalles Bibliográficos
Autores principales: Milde, Stefan, Brown, Guy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879728/
https://www.ncbi.nlm.nih.gov/pubmed/35216419
http://dx.doi.org/10.3390/ijms23042304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879728/
https://www.ncbi.nlm.nih.gov/pubmed/35216419
http://dx.doi.org/10.3390/ijms23042304

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