Evaluation of HSV-2 gE Binding to IgG-Fc and Application for Vaccine Development

Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to immune evasion by HSV. It has been reported that HS...

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Detalles Bibliográficos
Autores principales: Galli, Jennifer D., Horton, Melanie, Durr, Eberhard, Heidecker, Gwendolyn J., Freed, Daniel, Fridman, Arthur, Wang, Dai, Zhang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879737/
https://www.ncbi.nlm.nih.gov/pubmed/35214644
http://dx.doi.org/10.3390/vaccines10020184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879737/
https://www.ncbi.nlm.nih.gov/pubmed/35214644
http://dx.doi.org/10.3390/vaccines10020184

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