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Enhanced Differentiation Capacity and Transplantation Efficacy of Insulin-Producing Cell Clusters from Human iPSCs Using Permeable Nanofibrous Microwell-Arrayed Membrane for Diabetes Treatment

Although pancreatic islet transplantation is a potentially curative treatment for insulin-dependent diabetes, a shortage of donor sources, low differentiation capacity, and transplantation efficacy are major hurdles to overcome before becoming a standard therapy. Stem cell-derived insulin-producing...

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Detalles Bibliográficos
Autores principales: Shim, In Kyong, Lee, Seong Jin, Lee, Yu Na, Kim, Dohui, Goh, Hanse, Youn, Jaeseung, Jang, Jinah, Kim, Dong Sung, Kim, Song Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879814/
https://www.ncbi.nlm.nih.gov/pubmed/35214135
http://dx.doi.org/10.3390/pharmaceutics14020400