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Enhanced Differentiation Capacity and Transplantation Efficacy of Insulin-Producing Cell Clusters from Human iPSCs Using Permeable Nanofibrous Microwell-Arrayed Membrane for Diabetes Treatment
Although pancreatic islet transplantation is a potentially curative treatment for insulin-dependent diabetes, a shortage of donor sources, low differentiation capacity, and transplantation efficacy are major hurdles to overcome before becoming a standard therapy. Stem cell-derived insulin-producing...
Autores principales: | Shim, In Kyong, Lee, Seong Jin, Lee, Yu Na, Kim, Dohui, Goh, Hanse, Youn, Jaeseung, Jang, Jinah, Kim, Dong Sung, Kim, Song Cheol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879814/ https://www.ncbi.nlm.nih.gov/pubmed/35214135 http://dx.doi.org/10.3390/pharmaceutics14020400 |
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