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Characterizing the Drug-Release Enhancement Effect of Surfactants on Megestrol-Acetate-Loaded Granules

In this study, the effect of Cremophor(®) RH 40 (CR 40) classic micelles and Soluplus(®) (SP) polymeric micelles were investigated on a novel granule-type drug-delivery system containing megestrolacetate (MGA). Using a risk assessment-based approach on the formulation via melt technology resulted in...

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Detalles Bibliográficos
Autores principales: Katona, Gábor, Sipos, Bence, Ambrus, Rita, Csóka, Ildikó, Szabó-Révész, Piroska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879843/
https://www.ncbi.nlm.nih.gov/pubmed/35215226
http://dx.doi.org/10.3390/ph15020113