In Silico Searching for Alternative Lead Compounds to Treat Type 2 Diabetes through a QSAR and Molecular Dynamics Study

Free fatty acid receptor 1 (FFA1) stimulates insulin secretion in pancreatic β-cells. An advantage of therapies that target FFA1 is their reduced risk of hypoglycemia relative to common type 2 diabetes treatments. In this work, quantitative structure–activity relationship (QSAR) approach was used to...

Descripción completa

Detalles Bibliográficos
Autores principales: Cabrera, Nicolás, Cuesta, Sebastián A., Mora, José R., Calle, Luis, Márquez, Edgar A., Kaunas, Roland, Paz, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879932/
https://www.ncbi.nlm.nih.gov/pubmed/35213965
http://dx.doi.org/10.3390/pharmaceutics14020232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879932/
https://www.ncbi.nlm.nih.gov/pubmed/35213965
http://dx.doi.org/10.3390/pharmaceutics14020232

Ejemplares similares