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In Silico Searching for Alternative Lead Compounds to Treat Type 2 Diabetes through a QSAR and Molecular Dynamics Study

Free fatty acid receptor 1 (FFA1) stimulates insulin secretion in pancreatic β-cells. An advantage of therapies that target FFA1 is their reduced risk of hypoglycemia relative to common type 2 diabetes treatments. In this work, quantitative structure–activity relationship (QSAR) approach was used to...

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Detalles Bibliográficos
Autores principales:	Cabrera, Nicolás, Cuesta, Sebastián A., Mora, José R., Calle, Luis, Márquez, Edgar A., Kaunas, Roland, Paz, José Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879932/ https://www.ncbi.nlm.nih.gov/pubmed/35213965 http://dx.doi.org/10.3390/pharmaceutics14020232

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