Antiviral Targeting of Varicella Zoster Virus Replication and Neuronal Reactivation Using CRISPR/Cas9 Cleavage of the Duplicated Open Reading Frames 62/71

Varicella Zoster Virus (VZV) causes Herpes Zoster (HZ), a common debilitating and complicated disease affecting up to a third of unvaccinated populations. Novel antiviral treatments for VZV reactivation and HZ are still in need. Here, we evaluated the potential of targeting the replicating and react...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Betty W., Yee, Michael B., Goldstein, Ronald S., Kinchington, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880005/
https://www.ncbi.nlm.nih.gov/pubmed/35215971
http://dx.doi.org/10.3390/v14020378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880005/
https://www.ncbi.nlm.nih.gov/pubmed/35215971
http://dx.doi.org/10.3390/v14020378

Ejemplares similares