A Simple UPLC/MS-MS Method for Simultaneous Determination of Lenvatinib and Telmisartan in Rat Plasma, and Its Application to Pharmacokinetic Drug-Drug Interaction Study

Lenvatinib is a multi-targeted tyrosine kinase inhibitor that inhibits tumor angiogenesis, but hypertension is the most common adverse reaction. Telmisartan is an angiotensin receptor blocker used to treat hypertension. In this study, a simple ultra-performance liquid chromatography-tandem mass spec...

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Detalles Bibliográficos
Autores principales: Cui, Yanjun, Li, Ying, Li, Xiao, Fan, Liju, He, Xueru, Fu, Yuhao, Dong, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880132/
https://www.ncbi.nlm.nih.gov/pubmed/35209080
http://dx.doi.org/10.3390/molecules27041291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880132/
https://www.ncbi.nlm.nih.gov/pubmed/35209080
http://dx.doi.org/10.3390/molecules27041291

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