Recombinant HBsAg of the Wild-Type and the G145R Escape Mutant, included in the New Multivalent Vaccine against Hepatitis B Virus, Dramatically Differ in their Effects on Leukocytes from Healthy Donors In Vitro

Immune-escape hepatitis B virus (HBV) mutants play an important role in HBV spread. Recently, the multivalent vaccine Bubo(®)-Unigep has been developed to protect against both wild-type HBV and the most significant G145R mutant. Here, we compared the effects of recombinant HBsAg antigens, wild-type...

Descripción completa

Detalles Bibliográficos
Autores principales: Konopleva, Maria V., Borisova, Vera N., Sokolova, Maria V., Semenenko, Tatyana A., Suslov, Anatoly P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880183/
https://www.ncbi.nlm.nih.gov/pubmed/35214692
http://dx.doi.org/10.3390/vaccines10020235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880183/
https://www.ncbi.nlm.nih.gov/pubmed/35214692
http://dx.doi.org/10.3390/vaccines10020235

Ejemplares similares