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Lactate-Loaded Nanoparticles Induce Glioma Cytotoxicity and Increase the Survival of Rats Bearing Malignant Glioma Brain Tumor

A glioblastoma is an aggressive form of a malignant glial-derived tumor with a poor prognosis despite multimodal therapy approaches. Lactate has a preponderant role in the tumor microenvironment, playing an immunoregulatory role as well as being a carbon source for tumor growth. Lactate homeostasis...

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Detalles Bibliográficos
Autores principales: Chavarria, Víctor, Ortiz-Islas, Emma, Salazar, Alelí, Pérez-de la Cruz, Verónica, Espinosa-Bonilla, Alejandra, Figueroa, Rubén, Ortíz-Plata, Alma, Sotelo, Julio, Sánchez-García, Francisco Javier, Pineda, Benjamín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880216/
https://www.ncbi.nlm.nih.gov/pubmed/35214059
http://dx.doi.org/10.3390/pharmaceutics14020327