Model-Based Equivalent Dose Optimization to Develop New Donepezil Patch Formulation

Donepezil patch was developed to replace the original oral formulation. To accurately describe the pharmacokinetics of donepezil and investigate compatible doses between two formulations, a population pharmacokinetic model for oral and transdermal patches was built based on a clinical study. Plasma...

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Detalles Bibliográficos
Autores principales: Jung, Woojin, Jung, Heeyoon, Vu, Ngoc-Anh Thi, Kim, Gwan-Young, Kim, Gyoung-Won, Chae, Jung-woo, Kim, Taeheon, Yun, Hwi-yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880217/
https://www.ncbi.nlm.nih.gov/pubmed/35213976
http://dx.doi.org/10.3390/pharmaceutics14020244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880217/
https://www.ncbi.nlm.nih.gov/pubmed/35213976
http://dx.doi.org/10.3390/pharmaceutics14020244

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