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Functional EL-HN Fragment as a Potent Candidate Vaccine for the Prevention of Botulinum Neurotoxin Serotype E

Clostridium botulinum produces botulinum neurotoxin (BoNT), which is the most toxic known protein and the causative agent of human botulism. BoNTs have similar structures and functions, comprising three functional domains: catalytic domain (L), translocation domain (HN), and receptor-binding domain...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Lu, Jiansheng, Tan, Xiao, Wang, Rong, Xu, Qing, Yu, Yunzhou, Yang, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880310/
https://www.ncbi.nlm.nih.gov/pubmed/35202162
http://dx.doi.org/10.3390/toxins14020135