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Effect of GSTA1 Variants on Busulfan-Based Conditioning Regimen Prior to Allogenic Hematopoietic Stem-Cell Transplantation in Pediatric Asians

Busulfan is widely used as a chemotherapy treatment before hematopoietic stem-cell transplantation (HSCT). However, the response of busulfan is highly variable and unpredictable, whereby the pharmacogenetic interference of glutathione S-transferase (GST) has strong evidence in Caucasians and some ad...

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Detalles Bibliográficos
Autores principales: Nguyen, Ai-Hoc, Biswas, Mohitosh, Puangpetch, Apichaya, Prommas, Santirhat, Pakakasama, Samart, Anurathapan, Usanarat, Rachanakul, Jiratha, Sukprasong, Rattanaporn, Nuntharadtanaphong, Nutthan, Jongjitsook, Nutcha, Hongeng, Suradej, Sukasem, Chonlaphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880478/
https://www.ncbi.nlm.nih.gov/pubmed/35214132
http://dx.doi.org/10.3390/pharmaceutics14020401