The p97 Inhibitor UPCDC-30245 Blocks Endo-Lysosomal Degradation

The diverse modes of action of small molecule inhibitors provide versatile tools to investigate basic biology and develop therapeutics. However, it remains a challenging task to evaluate their exact mechanisms of action. We identified two classes of inhibitors for the p97 ATPase: ATP competitive and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Feng, Li, Shan, Cheng, Kai-Wen, Rosencrans, William M., Chou, Tsui-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880557/
https://www.ncbi.nlm.nih.gov/pubmed/35215314
http://dx.doi.org/10.3390/ph15020204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880557/
https://www.ncbi.nlm.nih.gov/pubmed/35215314
http://dx.doi.org/10.3390/ph15020204

Ejemplares similares