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The p97 Inhibitor UPCDC-30245 Blocks Endo-Lysosomal Degradation
The diverse modes of action of small molecule inhibitors provide versatile tools to investigate basic biology and develop therapeutics. However, it remains a challenging task to evaluate their exact mechanisms of action. We identified two classes of inhibitors for the p97 ATPase: ATP competitive and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880557/ https://www.ncbi.nlm.nih.gov/pubmed/35215314 http://dx.doi.org/10.3390/ph15020204 |