Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet

Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this research was to design orally disintegrating tablets with self-nanoemulsifying properties (T-SNEDDS) to improve the Pioglitazone solubility and dissolution rate. Three liquid self-nanoemulsifying systems (L-SNEDDS...

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Detalles Bibliográficos
Autores principales: Teaima, Mahmoud, Hababeh, Sandra, Khanfar, Mai, Alanazi, Fares, Alshora, Doaa, El-Nabrawi, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880587/
https://www.ncbi.nlm.nih.gov/pubmed/35214157
http://dx.doi.org/10.3390/pharmaceutics14020425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880587/
https://www.ncbi.nlm.nih.gov/pubmed/35214157
http://dx.doi.org/10.3390/pharmaceutics14020425

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