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Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet
Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this research was to design orally disintegrating tablets with self-nanoemulsifying properties (T-SNEDDS) to improve the Pioglitazone solubility and dissolution rate. Three liquid self-nanoemulsifying systems (L-SNEDDS...
Autores principales: | Teaima, Mahmoud, Hababeh, Sandra, Khanfar, Mai, Alanazi, Fares, Alshora, Doaa, El-Nabrawi, Mohammed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880587/ https://www.ncbi.nlm.nih.gov/pubmed/35214157 http://dx.doi.org/10.3390/pharmaceutics14020425 |
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