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Facial Synthesis and Bioevaluation of Well-Defined OEGylated Betulinic Acid-Cyclodextrin Conjugates for Inhibition of Influenza Infection

Betulinic acid (BA) and its derivatives exhibit a variety of biological activities, especially their anti-HIV-1 activity, but generally have only modest inhibitory potency against influenza virus. The entry of influenza virus into host cells can be competitively inhibited by multivalent derivatives...

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Detalles Bibliográficos
Autores principales: Chen, Yingying, Wang, Xinchen, Ma, Xinyuan, Liang, Shuobin, Gao, Qianqian, Tretyakova, Elena V., Zhang, Yongmin, Zhou, Demin, Xiao, Sulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880671/
https://www.ncbi.nlm.nih.gov/pubmed/35208962
http://dx.doi.org/10.3390/molecules27041163