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NSG-Mice Reveal the Importance of a Functional Innate and Adaptive Immune Response to Overcome RVFV Infection

Rift Valley fever (RVF) is a zoonotic disease caused by RVF Phlebovirus (RVFV). The RVFV MP-12 vaccine strain is known to exhibit residual virulence in the case of a deficient interferon type 1 response. The hypothesis of this study is that virus replication and severity of lesions induced by the MP...

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Detalles Bibliográficos
Autores principales: Michaely, Lukas Mathias, Rissmann, Melanie, Keller, Markus, König, Rebecca, von Arnim, Felicitas, Eiden, Martin, Rohn, Karl, Baumgärtner, Wolfgang, Groschup, Martin, Ulrich, Reiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880686/
https://www.ncbi.nlm.nih.gov/pubmed/35215938
http://dx.doi.org/10.3390/v14020350