Caffeine and MDMA (Ecstasy) Exacerbate ER Stress Triggered by Hyperthermia

Drugs of abuse can cause local and systemic hyperthermia, a known trigger of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR). Another trigger of ER stress and UPR is ER calcium depletion, which causes ER exodosis, the secretion of ER-resident proteins. In rodent models, clu...

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Detalles Bibliográficos
Autores principales: Trychta, Kathleen A., Harvey, Brandon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880705/
https://www.ncbi.nlm.nih.gov/pubmed/35216090
http://dx.doi.org/10.3390/ijms23041974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880705/
https://www.ncbi.nlm.nih.gov/pubmed/35216090
http://dx.doi.org/10.3390/ijms23041974

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