Unexpected Enhancement of Cytotoxicity of Cisplatin in a Rat Kidney Proximal Tubular Cell Line Overexpressing Mitochondrial Glutathione Transport Activity

In previous studies, we identified the two principal transporters that mediate the uptake of glutathione (GSH) from cytoplasm into the mitochondrial matrix of rat kidney proximal tubular cells. We hypothesized that genetic modulation of transporter expression could markedly alter susceptibility of r...

Descripción completa

Detalles Bibliográficos
Autor principal: Lash, Lawrence H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880737/
https://www.ncbi.nlm.nih.gov/pubmed/35216119
http://dx.doi.org/10.3390/ijms23041993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880737/
https://www.ncbi.nlm.nih.gov/pubmed/35216119
http://dx.doi.org/10.3390/ijms23041993

Ejemplares similares