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Engineering His-Tagged Senecavirus A for One-Step Purification of Viral Antigens

Senecavirus A (SVA) is a picornavirus that causes vesicular disease in swine, and the inactivated vaccine is used to prevent and control SVA infection. To develop a new chromatography strategy for the purification and concentration of SVA vaccine antigens, we inserted a 6×His-tag at the VP1 C-termin...

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Detalles Bibliográficos
Autores principales: Fan, Junhao, Xiao, Peiyu, Kong, Dongni, Liu, Xinran, Meng, Liang, An, Tongqing, Cai, Xuehui, Wang, Haiwei, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880742/
https://www.ncbi.nlm.nih.gov/pubmed/35214628
http://dx.doi.org/10.3390/vaccines10020170