Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells, w...

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Detalles Bibliográficos
Autores principales: Whitburn, Jessica, Rao, Srinivasa R., Morris, Emma V., Tabata, Sho, Hirayama, Akiyoshi, Soga, Tomoyoshi, Edwards, James R., Kaya, Zeynep, Palmer, Charlotte, Hamdy, Freddie C., Edwards, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880772/
https://www.ncbi.nlm.nih.gov/pubmed/35213227
http://dx.doi.org/10.1126/sciadv.abf9096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880772/
https://www.ncbi.nlm.nih.gov/pubmed/35213227
http://dx.doi.org/10.1126/sciadv.abf9096

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