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Ultraefficient extracellular vesicle–guided direct reprogramming of fibroblasts into functional cardiomyocytes

Direct lineage conversion holds great promise in the regenerative medicine field for restoring damaged tissues using functionally engineered counterparts. However, current methods of direct lineage conversion, even those using virus-mediated transgenic expression of tumorigenic factors, are extremel...

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Detalles Bibliográficos
Autores principales: Kim, Hyosuk, Song, Byeong-Wook, Park, Soon-Jung, Choi, Seong Woo, Moon, Hanbyeol, Hwang, Ki-Chul, Kang, Sun-Woong, Moon, Sung-Hwan, Yang, Yoosoo, Kwon, Ick Chan, Kim, Sun Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880777/
https://www.ncbi.nlm.nih.gov/pubmed/35213232
http://dx.doi.org/10.1126/sciadv.abj6621