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Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase

Electron bifurcation enables thermodynamically unfavorable biochemical reactions. Four groups of bifurcating flavoenzyme are known and three use FAD to bifurcate. FeFe-HydABC hydrogenase represents the fourth group, but its bifurcation site is unknown. We report cryo-EM structures of the related NiF...

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Detalles Bibliográficos
Autores principales: Feng, Xiang, Schut, Gerrit J., Haja, Dominik K., Adams, Michael W. W., Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880783/
https://www.ncbi.nlm.nih.gov/pubmed/35213221
http://dx.doi.org/10.1126/sciadv.abm7546