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Proteasome inhibition-enhanced fracture repair is associated with increased mesenchymal progenitor cells in mice

The ubiquitin/proteasome system controls the stability of Runx2 and JunB, proteins essential for differentiation of mesenchymal progenitor/stem cells (MPCs) to osteoblasts. Local administration of proteasome inhibitor enhances bone fracture healing by accelerating endochondral ossification. However,...

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Detalles Bibliográficos
Autores principales:	Zhang, Hengwei, Li, Xing, Liu, Jiatong, Lin, Xi, Pei, Lingpeng, Boyce, Brendan F., Xing, Lianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880819/ https://www.ncbi.nlm.nih.gov/pubmed/35213543 http://dx.doi.org/10.1371/journal.pone.0263839

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