Multiple subregions within the caveolin-1 scaffolding domain inhibit fibrosis, microvascular leakage, and monocyte migration

The caveolin-1 scaffolding domain (CSD, amino acids 82–101 of caveolin-1) has been shown to suppress bleomycin-induced lung and skin fibrosis and angiotensin II (AngII)-induced myocardial fibrosis. To identify active subregions within CSD, we split its sequence into three slightly overlapping 8-amin...

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Detalles Bibliográficos
Autores principales: Reese, Charles F., Chinnakkannu, Panneerselvam, Tourkina, Elena, Hoffman, Stanley, Kuppuswamy, Dhandapani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880820/
https://www.ncbi.nlm.nih.gov/pubmed/35213624
http://dx.doi.org/10.1371/journal.pone.0264413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880820/
https://www.ncbi.nlm.nih.gov/pubmed/35213624
http://dx.doi.org/10.1371/journal.pone.0264413

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